Bo Li Laboratory Gut Remodeling and Regeneration

MUST Precision Regenerative Medicine Research Centre at the International Conference on Hirschsprung Disease in Genoa

On April 12, 2026, Vice President of Macau University of Science and Technology (MUST), Chair Prof. Paul Kwong Hang Tam, led faculty members and student representatives from the Precision Regenerative Medicine Research Centre to participate in the International Conference on Hirschsprung Disease (HSCR), held in Genoa, Italy.

Organized by the International Consortium on the Genetics of Hirschsprung Disease, the meeting brought together distinguished scholars from the Americas, Europe, Asia, and other regions. During the conference, Vice President Tam delivered a keynote lecture highlighting the major scientific contributions of human genetics research to the field of Hirschsprung disease, the key challenges currently facing the field, and future directions for development. The conference focused on in-depth exchanges across multiple areas, including the genetic basis of HSCR, as well as its clinical and surgical management, systematically showcasing the latest research advances. These discussions underscored that HSCR research is evolving from single-gene and candidate-gene studies toward more comprehensive approaches involving genomics, transcriptomics, and disease stratification, thereby opening new directions for precision diagnosis, mechanistic investigation, and individualized intervention.

At the conference, Assistant Professor Bo Li from the Precision Regenerative Medicine Research Centre delivered an academic presentation entitled “HAEC and stromal-epithelial regenerative cross-talk.” Drawing on the team’s research foundation in the intestinal microenvironment, stromal remodeling, and regenerative repair, the presentation introduced new ideas regarding HSCR-associated enterocolitis and impaired tissue repair.

ENS 2026 Leuven Meeting

Earlier, Assistant Professor Li also attended the ENS 2026 Leuven meeting in Belgium, where he engaged in extensive discussions with international colleagues on frontier topics including enteric nervous system development, Hirschsprung disease, the pathogenesis of HAEC, and regenerative medicine.

This series of conference participations further enhanced the international visibility and engagement of the Precision Regenerative Medicine Research Centre under the Faculty of Medicine at MUST in the fields of intestinal development and regenerative medicine. It also strengthened collaborative ties with international peers in HSCR genetics, disease mechanisms, and translational research, laying a solid foundation for further integrating related research at MUST into the global academic network and increasing its academic influence.

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