Dr. Bo Li is an Assistant Professor at the Precision Regenerative Medicine Research Centre (PRMRC) at Macau University of Science and Technology (MUST). His research focuses on the mechanisms of gut remodeling and regeneration across congenital disorders, acquired intestinal injury, and systemic disease states. His work integrates stem cell biology, organoid and assembloid models, human tissues and patient-derived systems, experimental animal models, spatial and single-cell omics, and regenerative therapeutic strategies to understand disease mechanisms and identify pathways for tissue repair.
Academic Positions
Assistant Professor, 2026–present Precision Regenerative Medicine Research Centre Macau University of Science and Technology
Senior Research Associate, 2020–2026 The Hospital for Sick Children, Toronto
Postdoctoral Fellow, 2014–2020 The Hospital for Sick Children, Toronto Department of Surgery, University of Toronto
Associate Professor, 2009–2014 Liaoning He Medical University
Education
PhD in Cell and Developmental Biology (2005–2009) University College London, UK
MRes in Biomedical Sciences (2004–2005) University of Nottingham, UK
Bachelor’s Degree in Biopharmaceutical Engineering (2000–2004) Shenyang Pharmaceutical University, China
Research Interests
- Gut remodeling and regeneration across development, injury, and disease
- Congenital gut disorders, including Hirschsprung disease (HSCR) and anorectal malformations (ARM)
- Acquired intestinal injury, including necrotizing enterocolitis (NEC) and inflammatory bowel disease (IBD)
- Stromal, vascular, immune, and neural microenvironment regulation of tissue repair
- Organoid, assembloid, and multi-omics approaches for regenerative biology and translational therapy
Selected Achievements
- Author of 95+ peer-reviewed publications in intestinal biology, regenerative medicine, and pediatric disease research
- Publications in leading journals including Science Translational Medicine, Nature Communications, Immunity, and Cellular and Molecular Gastroenterology and Hepatology
- Recipient of multiple peer-reviewed research grants and international awards in regenerative and pediatric disease research
- Editorial and reviewer contributions to journals in gastroenterology, regenerative medicine, and developmental biology
Selected Honors and Awards
- Thrasher Research Fund Early Career Award
- Prem Puri Prize, International Symposium for Paediatric Surgical Research